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. 2021 Nov 11;12:773241. doi: 10.3389/fphar.2021.773241

TABLE 3.

Comparison of HRCT within 4–6 months.

Drug group (n = 47) Control group (n = 58)
Baseline 4–6 months later P-value D-valuea Baseline 4–6 months later P-value D-valuea P-valueb
Severity of bronchiectasis 1.91 ± 0.75 1.81 ± 0.80 0.467 0.11 ± 0.37 2.05 ± 0.74 2.03 ± 0.75 0.903 0.02 ± 0.13 0.087
Peribronchial thickening 2.11 ± 0.67 1.64 ± 0.67 0.001 0.47 ± 0.80 2.10 ± 0.67 1.90 ± 0.69 0.104 0.21 ± 0.52 0.006
Extent of bronchiectasis (No. of BP segments) 1.60 ± 0.71c 1.60 ± 0.71d 1 0 ± 0.21 1.97 ± 0.88 1.97 ± 0.88 1 0 ± 0 1
Extent of mucous plugging (No. of BP segments) 0.98 ± 0.79c 0.47 ± 0.62 0.001 0.51 ± 0.59 0.52 ± 0.57 0.40 ± 0.53 0.246 0.12 ± 0.38 <0.001
Sacculations or abscesses (No. of BP segments) 0.53 ± 0.72 0.28 ± 0.58d 0.047 0.26 ± 0.44 0.60 ± 0.53 0.45 ± 0.54 0.105 0.16 ± 0.37 0.204
Generations of bronchial divisions involved (bronchiectasis/plugging) 2.57 ± 0.68 2.55 ± 0.75 0.982 0.02 ± 0.15 2.69 ± 0.57 2.69 ± 0.57 1 0 ± 0 0.267
No. of bullae 0.11 ± 0.52 0.11 ± 0.52 1 0 ± 0 0.21 ± 0.49 0.21 ± 0.49 1 0 ± 0 1
Emphysema (No. of BP segments) 0.34 ± 0.73 0.32 ± 0.69 0.960 0.02 ± 0.15 0.16 ± 0.41 0.16 ± 0.41 1 0 ± 0 0.267
Collapse/consolidation 1.11 ± 0.67 0.66 ± 0.73 0.002 0.45 ± 0.77 1.02 ± 0.69 0.72 ± 0.74 0.025 0.29 ± 0.59 0.133
Bhalla score 13.74 ± 3.72 15.57 ± 3.60 0.017 −1.83 ± 1.62 13.69 ± 2.89 14.48 ± 2.85 0.139 −0.79 ± 1.37 <0.001

Data are presented as mean ± SD except as otherwise noted. HRCT, high-resolution computed tomography. No, number and BP, bronchopulmonary.

a

D-value, difference value, the difference between baseline and 4–6 months later.

b

The p-value of the d-value between two groups.

c

There were statistical differences between two groups during exacerbation (p < 0.05), the p-values of others were more than 0.05.

d

There were statistical differences between two groups 4–6 months later (p < 0.05), the p-values of others were more than 0.05.