TABLE 3.
Comparison of HRCT within 4–6 months.
| Drug group (n = 47) | Control group (n = 58) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | 4–6 months later | P-value | D-valuea | Baseline | 4–6 months later | P-value | D-valuea | P-valueb | |
| Severity of bronchiectasis | 1.91 ± 0.75 | 1.81 ± 0.80 | 0.467 | 0.11 ± 0.37 | 2.05 ± 0.74 | 2.03 ± 0.75 | 0.903 | 0.02 ± 0.13 | 0.087 |
| Peribronchial thickening | 2.11 ± 0.67 | 1.64 ± 0.67 | 0.001 | 0.47 ± 0.80 | 2.10 ± 0.67 | 1.90 ± 0.69 | 0.104 | 0.21 ± 0.52 | 0.006 |
| Extent of bronchiectasis (No. of BP segments) | 1.60 ± 0.71c | 1.60 ± 0.71d | 1 | 0 ± 0.21 | 1.97 ± 0.88 | 1.97 ± 0.88 | 1 | 0 ± 0 | 1 |
| Extent of mucous plugging (No. of BP segments) | 0.98 ± 0.79c | 0.47 ± 0.62 | 0.001 | 0.51 ± 0.59 | 0.52 ± 0.57 | 0.40 ± 0.53 | 0.246 | 0.12 ± 0.38 | <0.001 |
| Sacculations or abscesses (No. of BP segments) | 0.53 ± 0.72 | 0.28 ± 0.58d | 0.047 | 0.26 ± 0.44 | 0.60 ± 0.53 | 0.45 ± 0.54 | 0.105 | 0.16 ± 0.37 | 0.204 |
| Generations of bronchial divisions involved (bronchiectasis/plugging) | 2.57 ± 0.68 | 2.55 ± 0.75 | 0.982 | 0.02 ± 0.15 | 2.69 ± 0.57 | 2.69 ± 0.57 | 1 | 0 ± 0 | 0.267 |
| No. of bullae | 0.11 ± 0.52 | 0.11 ± 0.52 | 1 | 0 ± 0 | 0.21 ± 0.49 | 0.21 ± 0.49 | 1 | 0 ± 0 | 1 |
| Emphysema (No. of BP segments) | 0.34 ± 0.73 | 0.32 ± 0.69 | 0.960 | 0.02 ± 0.15 | 0.16 ± 0.41 | 0.16 ± 0.41 | 1 | 0 ± 0 | 0.267 |
| Collapse/consolidation | 1.11 ± 0.67 | 0.66 ± 0.73 | 0.002 | 0.45 ± 0.77 | 1.02 ± 0.69 | 0.72 ± 0.74 | 0.025 | 0.29 ± 0.59 | 0.133 |
| Bhalla score | 13.74 ± 3.72 | 15.57 ± 3.60 | 0.017 | −1.83 ± 1.62 | 13.69 ± 2.89 | 14.48 ± 2.85 | 0.139 | −0.79 ± 1.37 | <0.001 |
Data are presented as mean ± SD except as otherwise noted. HRCT, high-resolution computed tomography. No, number and BP, bronchopulmonary.
D-value, difference value, the difference between baseline and 4–6 months later.
The p-value of the d-value between two groups.
There were statistical differences between two groups during exacerbation (p < 0.05), the p-values of others were more than 0.05.
There were statistical differences between two groups 4–6 months later (p < 0.05), the p-values of others were more than 0.05.