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. 2021 Dec 1;2021(12):CD013776. doi: 10.1002/14651858.CD013776.pub2

Comparison 4. Blue light versus white light—subgroup analysis of 5‐ALA versus HAL (post hoc).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 Time to disease recurrence 15 2994 Hazard Ratio (IV, Random, 95% CI) 0.66 [0.54, 0.81]
4.1.1 5‐ALA 6 1430 Hazard Ratio (IV, Random, 95% CI) 0.76 [0.57, 1.00]
4.1.2 HAL 9 1564 Hazard Ratio (IV, Random, 95% CI) 0.60 [0.45, 0.78]
4.2 Time to disease progression 9 2200 Hazard Ratio (IV, Random, 95% CI) 0.77 [0.63, 0.96]
4.2.1 5‐ALA 5 1239 Hazard Ratio (IV, Random, 95% CI) 0.72 [0.47, 1.11]
4.2.2 HAL 4 961 Hazard Ratio (IV, Random, 95% CI) 0.69 [0.48, 0.98]