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Mediation analysis of A-B) the relationship between age and LDL-P by serine and C-D) the relationship between age and large LDL-P by glutamate. a, c and c’ represent the effects (regression coefficient) of age on the corresponding LMWM or lipoprotein parameter, and b represents the effect (regression coefficient) of a particular LMWM on the corresponding lipoprotein parameter. The covariates have been omitted for visualization purposes.
