Table 4.

List of significant associations (p-value < 0.05/31) between age and metabolomic features, including the annotated LMWMs and the covariates that were kept in the final regression model.

Metabolomic feature (ppm)	Annotated LMWM	Covariates	β	SE	p-value
3.977	Serine	BMI	−0.018	0.005	0.0002
3.949	Serine	BMI, SBP	−0.018	0.005	0.0003
2.047	Glutamate	SBP	−0.017	0.005	0.0011
1.057	Isobutyrate	SBP	0.016	0.005	0.0012
1.026	Valine	BMI	−0.018	0.005	0.0001
1.015	Valine	BMI	−0.019	0.005	0.0001
0.993	Isoleucine	BMI	−0.018	0.005	0.0002
0.975	Valine	BMI	−0.017	0.005	0.0003
0.963	Valine	BMI	−0.018	0.005	0.0001

LMWM: low molecular weight metabolite; β: regression coefficient; SE: standard error; BMI: body mass index; SBP: systolic blood pressure.