Table 2.
Microbiology of Organisms Reported in the PADIT Trial
| Microorganism | Total
(n = 209), No. (%) |
Conventional (n = 116), No. (%) | Incremental (n = 93), No. (%) | P Valuea |
|---|---|---|---|---|
| Gram-positive bacteria | 188 (90.0) | 104 (89.7) | 84 (90.3) | .82 |
| Staphylococcus aureus | 75 (35.9) | 36 (31.0) | 39 (41.9) | .36 |
| Coagulase-negative Staphylococcus | 82 (39.2) | 54 (46.6) | 28 (30.1) | .04 |
| Streptococcus pneumoniae | 1 (0.5) | 1 (0.9) | 0 | - |
| Enterococcus spp. | 4 (1.9) | 0 | 4 (4.3) | - |
| Viridans streptococci | 5 (2.4) | 5 (4.3) | 0 | - |
| Other streptococci | 2 (1.0) | 0 | 2 (2.2) | - |
| Proprionibacterium spp.b | 12 (5.7) | 5 (4.3) | 7 (7.5) | .29 |
| Other gram-positive bacteria | 7 (3.3) | 3 (2.6) | 4 (4.3) | - |
| Gram-negative bacteria | 17 (8.1) | 9 (7.8) | 8 (8.6) | .67 |
| Escherichia coli | 1 (0.5) | 1 (0.9) | 0 | - |
| Klebsiella spp. | 1 (0.5) | 1 (0.9) | 0 | - |
| Serratia spp. | 2 (1.0) | 2 (1.7) | 0 | - |
| Enterobacter spp. | 4 (1.9) | 1 (0.9) | 3 (3.2) | - |
| Other Enterobacteriaceae | 1 (0.5) | 0 | 1 (1.1) | - |
| Pseudomonas aeruginosa | 5 (2.4) | 2 (1.7) | 3 (3.2) | - |
| Nonfermenting gram-negative bacteria | 2 (1.0) | 2 (1.7) | 0 | - |
| Other gram-negative bacteria | 1 (0.5) | 0 | 1 (1.1) | - |
| Other pathogens | 4 (1.9) | 3 (2.6) | 1 (1.1) | - |
| Anaerobic bacteria (other than Proprionibacterium) | 2 (1.0) | 2 (1.7) | 0 | - |
| Candida albicans | 2 (1.0) | 1 (0.9) | 1 (1.1) | - |
Abbreviation: PADIT, Prevention of Arrhythmia Device Infection Trial.
P values were calculated for the variables with at least 10 cases using a logistic mixed model to account for underlying correlation among microorganisms detected in the same patient.
Includes Proprionibacterium spp. and Cutibacterium acnes (formerly known as P. acnes) (Table 3).