Table 2.

The univariate and multivariate Cox regression analysis exploring the association of SII tertile with short-term mortality of critically ill patients with CHF.

	Crude		Model I		Model II
	HR (95%CIs)	FDR	HR (95%CIs)	FDR	HR (95%CIs)	FDR
30-day all-cause mortality
SII (tertile)
<1144.28	1 (ref)		1 (ref)		1 (ref)
≥1144.28, <2730.11	1.17 (0.99, 1.38)	0.101	1.14 (0.97, 1.35)	0.134	1.05 (0.89, 1.25)	0.524
≥2730.11	1.73 (1.48, 2.03)	0.003	1.63 (1.40, 1.91)	0.003	1.23 (1.04, 1.45)	0.022
P for trend	<0.001		<0.001		<0.001
90-day all-cause mortality
SII (tertile)
<1144.28	1 (ref)		1 (ref)		1 (ref)
≥1144.28, <2730.11	1.12 (0.97, 1.28)	0.171	1.10 (0.96, 1.27)	0.202	1.02 (0.88, 1.17)	0.820
≥2730.11	1.65 (1.45, 1.88)	0.003	1.57 (1.38, 1.79)	0.003	1.21 (1.06, 1.39)	0.010
P for trend	<0.001		<0.001		<0.001
Hospital all-cause mortality
SII (tertile)
<1144.28	1 (ref)		1 (ref)		1 (ref)
≥1144.28, <2730.11	1.27 (1.06, 1.52)	0.016	1.21 (1.01, 1.45)	0.042	1.17 (0.97, 1.40)	0.096
≥2730.11	1.61 (1.36, 1.91)	0.003	1.45 (1.22, 1.72)	0.003	1.26 (1.05, 1.50)	0.017
P for trend	<0.001		<0.001		<0.001

Crude model was adjusted for none.

Model I was adjusted for age, gender, and race.

Model II was adjusted for age, gender, race, heart rate, blood urea nitrogen, albumin, troponin T, NT-proBNP, urine output of first day, cardiac index, the type of first ICU admission, the use of mechanical ventilation and vasopressor, pneumonia, and liver diseases.

SII, Systemic immune-inflammation index; CHF, congestive heart failure; HR, hazard ratio; CI, confidence interval. FDR, false discovery rate.