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. 2021 Nov 12;8:753133. doi: 10.3389/fcvm.2021.753133

Table 3.

The univariate and multivariate Logistic regression analysis exploring the association of SII tertile with readmission and MACEs of critically ill patients with CHF.

Crude Model I Model II
OR (95%CIs) FDR OR (95%CIs) FDR OR (95%CIs) FDR
Readmission
      SII (tertile)
            <1144.28 1 (ref) 1 (ref) 1 (ref)
            ≥1144.28, <2730.11 0.91 (0.77, 1.07) 0.581 0.94 (0.80, 1.11) 0.581 0.94 (0.80, 1.11) 0.581
            ≥2730.11 0.88 (0.75, 1.04) 0.581 0.93 (0.78, 1.10) 0.581 0.97 (0.81, 1.15) 0.703
P for trend <0.001 <0.001 <0.001
MACEs
      SII (tertile)
            <1144.28 1 (ref) 1 (ref) 1 (ref)
            ≥1144.28, <2730.11 1.17 (1.02, 1.35) 0.036 1.17 (1.02, 1.35) 0.036 0.92 (0.74, 1.13) 0.417
            ≥2730.11 2.01 (1.73, 2.32) 0.003 2.02 (1.74, 2.35) 0.003 1.39 (1.12, 1.73) 0.006
P for trend <0.001 <0.001 <0.001

Crude model was adjusted for none.

Model I was adjusted for age, gender, and race.

Model II was adjusted for age, gender, race, heart rate, blood urea nitrogen, albumin, troponin T, NT-proBNP, urine output of first day, cardiac index, the type of first ICU admission, the use of mechanical ventilation and vasopressor, pneumonia, and liver diseases.

SII, Systemic immune-inflammation index; CHF, congestive heart failure; OR, odds ratio; CI, confidence interval. FDR, false discovery rate.