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. 2021 Dec 1;146:105050. doi: 10.1016/j.jcv.2021.105050

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© 2021 The Authors. Published by Elsevier B.V.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Assay signals for antibodies against Spike of HCoVs in 117 serum specimens stratified by COVID-19 status. (A) The MSD assay's determined concentrations (AU/mL) for anti-HKU1-S IgG and anti-OC43-S. (B) Relative signal (RU) for both anti-HKU1-S and anti-OC43-S for SPRi. C) The MSD assay's determined concentrations (AU/L) for anti-229E-S IgG and anti-NL63-S IgG. Boldfaced line indicates the median of the distribution, with ends of the box representing the first and third quantiles of the distribution. Comparisons between serology status had p < 0.0001 by Wilcoxon rank-sum test.