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. 2021 Jul 15;42(12):2173–2180. doi: 10.1038/s41401-021-00722-4

Fig. 3. Changes in the trajectory of AP and discharge profiles in myelinated Ah-type BRNs isolated from OVI and OVX female rats before and after 100 nM G1 (selective agonist for estrogen membrane receptor GPR30) or G1 + 100 nM IbTX.

Fig. 3

The same pulse and step depolarization were applied before and after tests. a, b Representative AP recorded from identified Ah-type BRNs isolated from OVI and OVX female rats in the absence and presence of G1 or G1 + IbTX, respectively, under same brief pulse. c, d Representative recordings of repetitive discharge elicited by identical step-depolarization (120 pA) from same Ah-type BRNs of OVI and OVX female rats before and after G1 or G1 + IbTX treatments. The scale bars shown in d were applied for all step recordings.