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. 2021 Nov 30;11:23172. doi: 10.1038/s41598-021-02510-w

Table 3.

Associations of genetically predicted SHBG with ischemic heart disease in the UK Biobank using multivariable MR controlling for bioavailable testosterone in men.

Methods OR 95% CI p MVMR Egger intercept p
MVMR IVW 0.79 0.71, 0.88 1.1 × 10–5
MVMR median 0.83 0.73, 0.95 0.005
MVMR Egger 0.83 0.72, 0.94 0.005 0.19