Fig. 3.

OncoPrint showing the molecular characterisation of B-ALL samples — paediatric and adult patients and cell lines — according to CRLF2 gene expression status. Each column represents a patient or a cell line included in the study. CRLF2-r, CRLF2 rearrangement; PAR1 deletion, deletion in at least CSF2RA and IL3RA genes; IKZF1 plus, patients with IKZF1 deletions co-occurring with CDKN2A/B, PAX5 or PAR1 deletion in the absence of ERG deletion. CRLF2-r, JAK2, IKZF1 and PAR1 molecular features of cell lines were obtained from the Cancer Cell Line Encyclopedia (CCLE) database.