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Membrane cholesterol modulates the cyclic stretch-induced intracellular calcium responses in TM cells. A: Representative traces. B: Averaged results for 15 min cyclic stretch of control (black trace, bars), MβCD-treated (10 mM, blue trace, bar), and MβCD:cholesterol-treated (green trace, bar) TM cells. Stretch-evoked [Ca2+]i responses are modulated by membrane cholesterol (n = 21–77; N = 5–6). ∗∗∗∗P < 0.0001.
