Table 6.
Linear regression analysis of the factors influencing the number of antigens recognized by the study participants – AFIRM cohort.
| Covariate | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| Estimate | 95% CI | p value | Estimate | 95% CI | p value | |
| Age Group | ||||||
| 0 - 5 years | Ref. | . | . | Ref. | . | . |
| 6 - 10 years | 0.12 | 0.02, 0.21 | 0.0192 | 0.11 | 0.02, 0.20 | 0.0160 |
| 11 - 15 years | 0.31 | 0.21, 0.41 | <0.001 | 0.31 | 0.22, 0.40 | <0.001 |
| Asexual parasite positive | 0.23 | 0.14, 0.31 | <0.001 | 0.18 | 0.09, 0.26 | <0.001 |
| Gametocyte positive | 0.21 | 0.11, 0.31 | <0.001 | 0.10 | -0.002, 0.20 | 0.0578 |
| Sickle | ||||||
| Normal | Ref. | . | . | Ref. | . | . |
| Heterozygous | -0.06 | -0.18, 0.05 | 0.2925 | -0.06 | -0.15, 0.04 | 0.2593 |
| α - thalassaemia | ||||||
| Normal | Ref. | . | . | Ref. | . | . |
| Heterozygous | -0.05 | -0.14, 0.05 | 0.3634 | 0.004 | -0.08, 0.09 | 0.9297 |
| Homozygous | 0.06 | -0.06, 0.19 | 0.3303 | 0.08 | -0.03, 0.19 | 0.1386 |
| Season | ||||||
| Dry | Ref. | . | . | Ref. | . | . |
| Wet | -0.01 | -0.1, 0.07 | 0.7701 | 0.004 | -0.07, 0.08 | 0.8964 |
a
Parasitaemia as determined by PCR (18S QT-NASBA for all parasites and Pfs25 mRNA QT-NASBA for female gametocytes).
Ref., reference category. P values in bold are statistically significant (p<0.05).