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. 2021 Nov 30;11:23163. doi: 10.1038/s41598-021-02667-4

Table 2.

Liver perfusion parameters and histogram parameters for patients with IMCCs and HCCs.

Group Mean Value  ± SD P Value
HCCs (n = 54) IMCCs(n = 36) HCCs (n = 54) IMCCs (n = 36)
HAP (mean) − 0.001 − 0.014 0.049 0.042 0.059
HAP (0.1) − 0.018 − 0.034 0.057 0.059 0.062
HAP (0.25) − 0.010 − 0.024 0.0532 0.051 0.072
HAP (0.5) − 0.001 − 0.013 0.049 0.041 0.065
HAP (0.75) 0.007 − 0.002 0.044 0.035 0.064
HAP (0.9) 0.015 0.006 0.041 0.033 0.119
PVP (mean) 0.261 0.254 0.076 0.096 0.733
PVP (0.1) 0.188 0.155 0.077 0.094 0.079
PVP (0.25) 0.221 0.197 0.076 0.096 0.182
PVP (0.5) 0.260 0.250 0.077 0.099 0.609
PVP (0.75) 0.299 0.306 0.080 0.109 0.759
PVP (0.9) 0.335 0.356 0.084 0.122 0.389
AEF (mean) 0.594 0.536 0.124 0.120 0.001*
AEF (0.1) 0.511 0.420 0.089 0.116  < 0.001*
AEF (0.25) 0.548 0.475 0.091 0.090  < 0.001*
AEF (0.5) 0.587 0.518 0.107 0.083  < 0.001*
AEF (0.75) 0.630 0.567 0.140 0.080 0.005*
AEF (0.9) 0.678 0.616 0.198 0.102 0.040*
HAP(variance) 0.0002 0.0005 0.0003 0.002 0.607
HAP(skewness) 11.272 − 0.028 82.728 0.661 0.939
HAP(kurtosis) 130.846 3.674 936.972 1.360 0.329
PVP(variance) 0.004 0.008 0.003 0.010 0.009*
PVP(skewness) 6.122 0.257 44.687 0.645 0.121
PVP(kurtosis) 62.578 3.794 433.540 1.334 0.355
AEF(variance) 0.018 0.061 0.044 0.207 0.113
AEF(skewness) 1.597 3.295 4.107 7.032 0.435
AEF(kurtosis) 35.482 105.111 96.997 271.455 0.033*

*Statistically significant difference between the two groups (P < 0.05).

HAP hepatic artery perfusion (mL/100 mL/min), PVP portal vein perfusion (mL/100 mL/min), AEF arterial enhancement fraction (%), IMCC intrahepatic mass-forming cholangiocarcinoma, HCC hepatocellular carcinoma.