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Immunohistochemical staining and fluorescence in situ hybridization of ETV6-TNFRSF8 associated carcinoma. a Diffuse cytoplasmic immunostaining for pan-cytokeratin. b Diffuse nuclear immunostaining for p63. c The tumor is negative for p16. d Florescence in situ hybridization showing unbalanced ETV6 gene rearrangement with deletion of the centromeric signal (red), in cells with 2n, 3n, and 4n copies (polysomic) of ETV6 (red, centromeric; green, telomeric)
