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. 2021 Nov 30;11:23142. doi: 10.1038/s41598-021-02391-z

Table 1.

Demographic characteristics of M1 Stage IV gastric cancer patients by different treatment modalities from 2008 to 2015 in Taiwan.

Analysis variables Total Chemotherapy alone Surgery alone Chemotherapy + surgery Supportive care P-value
N (%)a N (%)a N (%)a N (%)a N (%)a
Total 5599 2963 (52.9)b 389 (6.9)b 1017 (18.2)b 1230 (22.0)b
Sex
Men 3429 (61.2) 1799 (60.7) 240 (61.7) 608 (59.8) 782 (63.6) 0.249
Women 2170 (38.8) 1164 (39.3) 149 (38.3) 409 (40.2) 448 (36.4)
Age at diagnosis (years)
 < 55 1334 (23.8) 867 (29.3) 52 (13.4) 299 (29.4) 116 (9.4) < 0.001
55–64 1207 (21.6) 710 (24.0) 57 (14.7) 296 (29.1) 144 (11.7)
65–74 1217 (21.7) 667 (22.5) 85 (21.9) 245 (24.1) 220 (17.9)
75 +  1841 (32.9) 719 (24.3) 195 (50.1) 177 (17.4) 750 (61.0)
Year of diagnosis
2008–2009 1218 (21.8) 596 (20.1) 98 (25.2) 214 (21.0) 310 (25.2) 0.001
2010–2011 1467 (26.2) 748 (25.2) 92 (23.7) 285 (28.0) 342 (27.8)
2012–2013 1421 (25.4) 777 (26.2) 102 (26.2) 261 (25.7) 281 (22.8)
2014–2015 1493 (26.7) 842 (28.4) 97 (24.9) 257 (25.3) 297 (24.1)
Tumor grade
Low grade 1036 (18.5) 470 (15.9) 105 (27.0) 229 (22.5) 232 (18.9) < 0.001
High grade 2947 (52.6) 1388 (46.8) 271 (69.7) 735 (72.3) 553 (45.0)
Undefined 1616 (28.9) 1105 (37.3) 13 (3.3) 53 (5.2) 445 (36.2)
Hospital level
Regional hospital 2100 (37.5) 1000 (33.7) 180 (46.3) 399 (39.2) 521 (42.4) < 0.001
Medical center 3499 (62.5) 1963 (66.3) 209 (53.7) 618 (60.8) 709 (57.6)
Surgical resection status
R0 978 (17.5) 0 256 (65.8) 722 (71.0) 0 < 0.001
R1 341 (6.1) 0 105 (27.0) 236 (23.2) 0
R2 87 (1.6) 0 28 (7.2) 59 (5.8) 0
No surgery 4193 (74.9) 2963 (100.0) 0 (0.0) 0 (0.0) 1230 (100.0)

aPercentages are vertically summed up to 100% for each analysis variable.

bPercentages are horizontally summed up to be 100%.