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. 2021 Nov 30;11:23142. doi: 10.1038/s41598-021-02391-z

Table 2.

Median overall survival and hazard ratio of M1 Stage IV gastric cancer patients by demographic characteristics and treatment modalities from 2008 to 2015 in Taiwan.

Median overall survival (OS) Univariate hazard ratio (HR)
Months 95% CI P-value HR 95% CI P-value
All patients 6.2 5.9–6.4
Sex
Men 6.0 5.8–6.3 0.073 1.00
Women 6.5 6.1–6.9 0.95 0.9–1.01 0.073
Age at diagnosis (years)
< 55 8.1 7.5–8.7 < 0.001 1.00
55–64 7.9 7.4–8.5 0.99 0.91–1.07 0.803
65–74 6.5 6.0–7.1 1.10 1.02–1.19 0.019
75 +  4.0 3.7–4.3 1.59 1.48–1.71 < 0.001
Year of diagnosis
2008–2009 5.7 5.3–6.1 0.001 1.00
2010–2011 6.1 5.7–6.5 0.91 0.84–0.98 0.016
2012–2013 6.8 6.3–7.3 0.86 0.79–0.93 < 0.001
2014–2015 6.3 5.8–6.7 0.91 0.84–0.99 0.022
Tumor grade
Low grade 7.3 6.6–7.9 < 0.001 1.00
High grade 6.4 6.1–6.8 1.22 1.13–1.31 < 0.001
Undefined 5.2 4.9–5.6 1.49 1.37–1.61 < 0.001
Hospital level
Regional hospital 5.4 5.0–5.7 < 0.001 1.00
Medical center 6.7 6.4–7.0 0.86 0.81–0.9 < 0.001