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HIF-1α expression and clinical outcome of Sorafenib treatment.
| HIF-1α mRNA expression | p | ||
|---|---|---|---|
| High (n = 26) | Low (n = 26) | ||
| TTP | 8.0 | 12.0 | 0.005 |
| 6.9–9.1 (M) | 10.9–13.1 (M) | ||
| OS | 10.0 | 14.0 | 0.032 |
| 6.8–13.2 (M) | 8.8–19.1 (M) | ||
TTP, time to progress; OS, overall survival; M, months.
