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. 2021 Nov 12;8:748225. doi: 10.3389/fmed.2021.748225

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Copyright © 2021 Ou, Tsai, Chen, Li, Tseng, Lee, Chang, Lin, Yang and Tarng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plasma Gal-3 predicts risk of annual change of eGFR in non-CKD patients whose eGFR > 60 ml/min/1.73 m². (A) Restricted cubic spline plots of the association between annual change of eGFR and plasma Gal-3 levels. The red line indicates the change of eGFR with the respective 95% confidence interval (gray area). (B) Annual change of eGFR according to tertile of plasma Gal-3 levels. Gal-3, Galectin-3; eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease.