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. 2021 Nov 12;8:748225. doi: 10.3389/fmed.2021.748225

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Copyright © 2021 Ou, Tsai, Chen, Li, Tseng, Lee, Chang, Lin, Yang and Tarng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kidney biopsy specimens for pathology and RNA sequencing analysis. (A) The algorithm of the collections of kidney biopsy specimens. (B) The associations between different pathological diagnoses and plasma Gal-3 levels. (C) The hierarchical clustering heat map shows the expression of different genes between fibrotic groups and non-fibrotic controls. Gal-3, galectin-3; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; MCD, minimal change disease; FSGS, focal segmental glomerulosclerosis; IgA, immunoglobulin A; DM, diabetes mellitus.