Table 1.
Clinical characteristics of our study participants stratified by tertile of plasma Gal-3 levels.
| Tertile of plasma Gal-3 levels | |||||
|---|---|---|---|---|---|
| All patients | Lowest tertile | Middle tertile | Highest tertile | P-value | |
| (n = 249) | (<610.7 pg/mL) | (610.8–1039.8 pg/mL) | (>1039.9 pg/mL) | ||
| (n = 83) | (n = 83) | (n = 83) | |||
| Age, years | 57.2 ± 16.3 | 54.3 ± 16.8 | 58.2 ± 17.1 | 59.0 ± 14.7 | 0.136 |
| Male sex, n (%) | 155 (62.3) | 48 (57.8) | 52 (62.7) | 55 (66.3) | 0.531 |
| Body mass index | 25.6 ± 4.6 | 25.9 ± 4.3 | 25.5 ± 5.0 | 25.3 ± 4.4 | 0.679 |
| Systolic blood pressure, mmHg | 136.8 ± 22.7 | 136.5 ± 24.2 | 133.2 ± 21.6 | 140.7 ± 22.0 | 0.106 |
| Diastolic blood pressure, mmHg | 77.2 ± 13.0 | 75.6 ± 12.5 | 77.4 ± 13.1 | 78.4 ± 13.5 | 0.370 |
| Diabetes mellitus, n (%) | 64 (25.7) | 23 (27.7) | 14 (16.9) | 27 (32.5) | 0.061 |
| Coronary artery disease, n (%) | 20 (8.0) | 6 (7.2) | 4 (4.8) | 10 (12.0) | 0.218 |
| Congestive heart failure, n (%) | 46 (18.5) | 17 (20.5) | 12 (14.5) | 17 (20.5) | 0.513 |
| Hypertension, n (%) | 105 (42.2) | 31 (37.3) | 31 (37.3) | 43 (51.8) | 0.093 |
| Dyslipidemia, n (%) | 47 (18.9) | 17 (20.5) | 17 (20.5) | 13 (15.7) | 0.657 |
| Malignancy, n (%) | 60 (24.1) | 21 (25.3) | 16 (19.3) | 23 (27.7) | 0.425 |
| LDL-C, mg/dL | 140.5 ± 85.6 | 142.6 ± 88.3 | 156.9 ± 98.6 | 120.4 ± 60.9 | 0.038† |
| Uric acid, mg/dL | 6.7 ± 2.2 | 6.7 ± 2.1 | 6.5 ± 2.2 | 7.1 ± 2.3 | 0.289 |
| Albumin, mg/dL | 3.2 ± 0.9 | 3.2 ± 0.9 | 3.2 ± 0.9 | 3.2 ± 0.8 | 0.879 |
| eGFR, mL/min/1.73 m2 | 45.1 ± 34.0 | 43.8 ± 33.9 | 54.7 ± 36.4 | 36.8 ± 29.3 | 0.003§ |
| UACR, g/g | 4.0 ± 5.4 | 4.4 ± 6.5 | 4.7 ± 6.8 | 3.4 ± 3.7 | 0.336 |
| UPCR, g/g | 5.3 ± 6.7 | 6.1 ± 6.7 | 5.2 ± 7.7 | 4.8 ± 5.5 | 0.480 |
†
Post-hoc test of LDL-C showed only a significant difference between middle tertile and highest tertile (P = 0.029).
§
Post-hoc test of eGFR showed only a significant difference between middle tertile and highest tertile (P = 0.002).
Gal-3, galectin-3; LDL-C, low density lipoprotein-cholesterol eGFR, estimated glomerular filtration rate; UACR, urine albumin-creatinine ratio; UPCR, urine protein-creatinine ratio.