Table 1.
Baseline demographic, medical, surgical and fibroid characteristics of all trial participants.
| Uterine Artery Embolization (n = 127) | Myomectomy (n = 127) | ||
|---|---|---|---|
| Demographics and obstetric history | |||
| Age, years | Mean (SD) | 40.2 (6.55), 127 | 42.7 (6.4), 127 |
| Ethnic Group | White (British/Other) | 59 (46%) | 57 (45%) |
| Black (Caribbean/African/other) | 48 (38%) | 54 (43%) | |
| South Asian (Indian/Pakistani/Bangladeshi) | 10 (8%) | 5 (4%) | |
| Mixed (White/Black/Asian/other) | 6 (5%) | 8 (6%) | |
| Other | 4 (3%) | 3 (2%) | |
| BMI, kg/m2 | Mean (SD), n | 28.2 (6.2), 119 | 28.1 (5.3), 123 |
| Desiring pregnancy at time of randomization | 61 (48%) | 61 (48%) | |
| Parity | Median [IQR], n | 0 [0,1], 125 | 1 [0,2], 127 |
| Gravida | Median [IQR], n | 1 [0,2], 125 | 2 [0,3], 127 |
| Fibroid assessment | |||
| Scanning modality to diagnose fibroidb | MRI | 89 (71%) | 99 (79%) |
| Ultrasound | 36 (29%) | 27 (21%) | |
| Not stated | 2 | 1 | |
| Location of largest fibroid | Submucosal | 6 (5%) | 14 (11%) |
| Submucosal (pedunculated) | 1 (1%) | 1 (1%) | |
| Subserosal | 30 (25%) | 21 (17%) | |
| Subserosal (pedunculated) | 6 (5%) | 5 (4%) | |
| Intramural | 74 (61%) | 81 (64%) | |
| Other | 4 (3%) | 0 (-) | |
| Not stated | 6 | 5 | |
| Longest dimension of largest fibroid, cma | <=7 | 64 (50%) | 64 (50%) |
| >7 | 63 (50%) | 63 (50%) | |
| Mean (SD) | 7.6 (3.2) | 7.7 (4.2) | |
| Number of fibroidsa | 1–3 | 84 (66%) | 84 (66%) |
| 4–10 | 37 (29%) | 37 (29%) | |
| >10 | 6 (5%) | 6 (5%) | |
| Median [IQR] | 2 [1,5] | 2 [1,5] | |
| Largest fibroid volume, cm3 | Mean (SD), n | 436 (594), 124 | 446 (548), 126 |
| Uterine volume, cm3 | Mean (SD), n | 1170 (1280), 118 | 1240 (1120), 118 |
| Medical and surgical history | |||
| Previous abdominal surgeryc | Caesarean section | 12 (9%) | 19 (15%) |
| Laparoscopy | 19 (15%) | 15 (12%) | |
| Endometrial ablation | 3 (2%) | 2 (2%) | |
| Appendectomy | 8 (6%) | 7 (6%) | |
| Sterilization | 4 (3%) | 5 (4%) | |
| Other | 10 (8%) | 15 (12%) | |
| Taking contraceptive/ hormonal treatments to control symptoms, at randomization | 75 (59%) | 73 (57%) | |
a
Minimisation variable;
b
More than one type of scan possible;
c
More than one previous abdominal surgery possible. Table reproduced from Manyonda 2020.