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Comparing ensembles relative to the optimum. For each protein (a: Hst5, b: Sic1, c: Tau and d: TIA1) we calculated the effective fraction of frames (shown here as φeff) between the weights obtained using the parameters in Table 1 and the weights obtained at all other combinations of r0 and δρ. White spots correspond to ensembles in which the iBME reweighting failed. Purple spots correspond to the minima for γ. To see this figure in color, go online.
