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Effect of the prior distribution. (a) Distributions of Rg of α-Synuclein sampled with flexible-meccano (FM), a99SB-disp (disp), and a03ws. (b) Reweighted Rg distributions, either from the optimal (lowest γ) δρ and r0 parameters for each ensemble (solid lines) or using the default values, we propose (δρ= 3.34 e/nm3 and r0 = 1.681 Å; dotted lines). To see this figure in color, go online.
