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. 2021 Nov 12;8(6):rbab061. doi: 10.1093/rb/rbab061

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — 3D-printed PCL/LAP scaffolds accelerated rat calvarial bone defect regeneration in vivo. Representative micro-CT images (a) and the BV/TV (b), BMD (c) and new bone formation rate (d) of each group. (e) Percentages of new bone formation on the histological sections. (f) Quantitative analysis of blood vessel areas. Representative images of H&E (g), Masson’s trichrome (h), Alizarin red S (i) staining and immunohistochemical images of CD31-positive cells in defect areas. Arrows indicate blood vessels. Pound signs (#) indicate PCL or PCL/5%LAP scaffolds. NB, newly formed bone. **P < 0.01 and ***P < 0.001