Table 3.

Functional classification of the proteins differentially expressed in the myocardium from patients with CCC, IC and DCM.

Function	Total prot.*	T. diff. prot.†	CCC/N		IC/N		DCM/N
			↑	↓	↑	↓	↑	↓
1. Structural and Contractile Proteins	32	25	7	13	4	5	8	10
2. Metabolism	86	60	19	32	16	6	19	29
2.1. Glycolysis	15	11	5	5	3	0	3	6
2.2. Lipid Metabolism/ß-Oxidation	11	7	0	6	1	1	1	2
2.3. Tricarboxylic Acid Cycle	8	7	1	4	1	0	2	3
2.4. Oxidative Phosphorylation and Electron Transport	18	14	5	8	5	2	4	8
2.5. Creatine Kinase System (Energy Transduction)	3	2	0	2	0	1	0	2
2.6. Other Metabolic Processes	31	19	8	7	6	2	9	8
3. Stress Response and Apoptosis	27	22	13	6	2	0	12	6
4. Immune Response	3	3	3	0	2	0	2	0
5. Cell Signaling	13	4	2	1	0	0	1	2
6. Transcription and Translation Processes	18	6	2	2	0	0	3	3
7. Transport	8	3	2	1	2	0	2	1
8. Proteasome-Ubiquitin Process	6	3	3	0	0	0	2	0
9. Other Functions	37	23	12	8	7	1	11	6
Total	230	149	63	63	33	12	60	57

*Total prot., Total number of proteins identified in each functional classification; ^†T. diff. prot., Total number of proteins in each functional classification that were found to be differentially expressed in the myocardium from patients with CCC, IC and DCM as compared to individuals without cardiomyopathies (N).

↑ means upregulated expression ↓ means downregulated expression.

Bold means the total number of protein in each column