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. 2021 Oct 25;41:101171. doi: 10.1016/j.eclinm.2021.101171

Table 4.

Effectiveness of Antidepressant across Strata

Antidepressant Number of Significant Predictors Number of Strata Number of Trimmed Strata Breslow Day Statistic for Homogeneity Common Odds Ratio (99% Confidence Interval)*
Amitriptyline 148 227,526 749 10,362 (p-value<0.0001) 1.25 (1.23 to 1.27)
Bupropion 163 662,577 2,371 193,397 (p-value<0.0001) 1.14 (1.13 to 1.15)
Citalopram 263 759,321 2,258 122,764 (p-value<0.0001) 1.03 (1.03 to 1.03)
Desvenlafaxine 116 64,650 239 14,275 (p-value<0.0001) 0.99 (0.98 to 1.01)
Doxepin 73 36,783 148 4,570 (p-value<0.0001) 1.16 (1.14 to 1.18)
Duloxetine 194 390,553 1,253 46,622 (p-value<0.0001) 1.06 (1.05 to 1.06)
Escitalopram 202 848,032 2,765 107,639 (p-value<0.0001) 1.07 (1.07 to 1.07)
Fluoxetine 187 669,013 2,237 149,309 (p-value<0.0001) 1.01 (1.01 to 1.02)
Mirtazapine 142 153,949 436 10,785 (p-value<0.0001) 1.09 (1.08 to 1.1)
Nortriptyline 74 62,961 254 5,015 (p-value<0.0001) 1.16 (1.14 to 1.18)
Paroxetine 204 390,144 1,230 55,010 (p-value<0.0001) 1.06 (1.05 to 1.06)
Ropinirole 76 51,933 184 4,168 (p-value<0.0001) 1.16 (1.15 to 1.18)
Sertraline 252 1,028,431 3,162 219,717 (p-value<0.0001) 1.02 (1.01 to 1.02)
Trazodone 113 331,735 1,258 81,815 (p-value<0.0001) 1.23 (1.22 to 1.25)
Venlafaxine 164 434,208 1,485 84,394 (p-value<0.0001) 1.00 (1 to 1.01)
Other 321 2,156,363 6,804 452,940 (p-value<0.0001) 1.02 (1.01 to 1.02)

No Common Odds Ratio Existed across Strata