Experimental and allelic separation workflow
Cell cycle sorted cells were extracted for RNA-seq, Bru-seq, and Hi-C (left to right, respectively). RNA-seq and Bru-seq data were allelicly phased via SNVs/InDels (left). SNV/InDel based imputation and haplotype phasing of Hi-C data using HaploHiC (right). These data provide quantitative measures of structure and function of the maternal and paternal genomes through the cell cycle. For all G2 labels after the cell cycle diagram, G2 includes both G2 and M.