Table 4.

Association of type 2 diabetes mellitus (T2DM) and/or hypertension (HTN) with combined vascular events and stroke compared with T2DM-only

	Combined vascular event (VE)		Stroke
	HR (95% CI)	P value	HR (95% CI)	P value
Unadjusted
T2DM-only	1 (reference)		1 (reference)
HTN-only	3.575 (3.296 to 3.877)	<0.0001	4.160 (3.701 to 4.675)	<0.0001
T2DM and HTN	2.821 (2.558 to 3.112)	<0.0001	2.883 (2.504 to 3.321)	<0.0001
Age- adjusted and sex-adjusted
T2DM-only	1 (reference)		1 (reference)
HTN-only	2.657 (2.447 to 2.885)	<0.0001	3.011 (2.676 to 3.389)	<0.0001
T2DM and HTN	2.062 (1.868 to 2.276)	<0.0001	2.063 (1.789 to 2.379)	<0.0001
Risk factors-adjusted
T2DM-only	1 (reference)		1 (reference)
HTN-only	2.435 (2.113 to 2.805)	<0.0001	2.868 (2.341 to 3.513)	<0.0001
T2DM and HTN	2.253 (1.876 to 2.706)	<0.0001	2.620 (2.031 to 3.380)	<0.0001

Risk factors include age, sex, triglycerides, total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol.

HTN, hypertension; T2DM, type 2 diabetes mellitus; VE, combined vascular event.