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Berberine regulated mitochondrial energy metabolism partially via upregulating FTO. After being treated by BER or BER/FB23-2 for 1, 3, or 7 days, PGC-1α mRNA (A), protein level (B), mitochondrial DNA content (C), and mitochondrial ATP synthesis (D) were measured. *p < 0.05, vs. mock group; *p < 0.05, vs. BER group.
