Table 1.
Characteristics of the 104 Patients
| Characteristic | Febrile Neutropenia (n = 97) |
Neutropenia Without Fever (n = 7) | ||
|---|---|---|---|---|
| Age, y, median | 7 | … | 6 | … |
| Age distribution, No. (%) | ||||
| ≤2 y | 17 | (17.5) | 1 | (16.7) |
| 3–5 y | 24 | (24.7) | 2 | (33.3) |
| 6–10 y | 22 | (22.7) | 3 | (50.0) |
| 11–15 y | 27 | (27.8) | 1 | (16.7) |
| ≥16 y | 7 | (7.2) | 0 | (0) |
| Sex, male, No. (%) | 67 | (69.0) | 4 | (57.1) |
| Cause of neutropenia, No. (%) | ||||
| Cancer chemotherapy | 80 | (82.5) | 5 | (71.4) |
| HSCT | 12 | (12.4) | 1 | (14.3) |
| Underlying disease | 5 | (5.2) | 1 | (14.3) |
| Primary medical condition, No. (%) | ||||
| Leukemia | 43 | (44.3) | 3 | (50.0) |
| Solid tumors | 34 | (35.1) | 2 | (33.3) |
| Bone marrow failure | 9 | (9.3) | 1 | (16.7) |
| Lymphoma | 5 | (5.2) | 0 | (0) |
| CNS tumors | 4 | (4.1) | 1 | (16.7) |
| Primary immunodeficiency | 2 | (2.1) | 0 | (0) |
| Clinical symptoms, No. (%) | ||||
| Oral | 16 | (16.5) | 1 | (14.3) |
| Skin | 5 | (5.2) | 0 | (0) |
| Gastrointestinal | 20 | (20.6) | 0 | (0) |
| Other(s) | 5 | (5.2) | 0 | (0) |
| Blood culture test positive, No. (%) | 10 | (10.3) | … | … |
Fifteen FN patients and three NE patients were excluded due to low quality of their samples for sequencing.
Abbreviations: CNS, central nervous system; HSCT, hematopoietic stem cell transplantation.