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Potential effect of leptin in activating TILs in the tumor microenvironment through the leptin receptor. The presence of TILs in the tumor microenvironment may be due, among other factors, to the action of leptin through binding to its receptor on T cells. PD-1, programmed death 1; TILs, tumor-infiltrating lymphocytes; PD-L1, programmed death-ligand 1; García-Estévez L ©.
