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. 2021 Nov 15;9:713925. doi: 10.3389/fcell.2021.713925

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Copyright © 2021 Wu, Li, Yang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene set enrichment analysis (GSEA) and lower half inhibitory centration (IC50) of chemotherapeutic drugs between the high- and low-risk group based on the pyroptosis-related lncRNA signature in TCGA-HCC. (A) GSEA results suggested that the two risk groups were mainly enriched in the tumor-, immune-, and metabolism-related pathways. (B) A low-risk score was related to an IC50 of chemotherapeutics such as bortezomib, and a high-risk score was related to docetaxel.