Table 4. Pharmacokinetic Parameters in the Male C57BL/6 Mouse for Compounds 20 and 22 after 3 mg/kg IP Administration^a.

Cpd	dose (mg/Kg)	HL (h)	Tmax (h)	Cmax (ng/mL)	AUClast (h*ng/mL)	AUCINF (h*ng/mL)	Vd (L/Kg)	Cl (L/h/Kg)
20	3	1.17	0.50	1610	2260	2323	2.18	1.29
22	3	5.2	2	3583	22543	23328	0.96	0.13

^aSee the Experimental Section and Tables S2 and S3 and Figures S8 and S9 in the Supporting Information