Figure 2.

Clinical and tumor characteristics. Cancer-specific features of early-onset colorectal EO-CRC and AO-CRC by age at diagnosis: 35 years and younger, 36-49 (EO-CRC) and 50 years and older AO-CRC. A) Comparison of demographic, clinical, and tumor characteristics demonstrates that there is no significant difference in several characteristics, including sex and tumor grade distribution. Median body mass index was lower in the 35 years and younger cohort than in the AO-CRC cohort. B) Frequency of cancer-related presenting symptoms. C) Colorectal primary tumor location. AO = average onset; CRC = colorectal cancer; EO = early-onset; NOS = not otherwise specified.