Figure 2.

A) Reader 2 selected 1 pulmonary and 1 osseous metastasis as target lesions in the same patient, which yielded a 13% increase on the sum of the longest axial diameters based on unidimensional RECIST measurements between baseline (left) and follow-up examination (right). B) Based on volumetric RECIST measurements, a 49% increase in the sum of target lesion volumes was noted between baseline (left) and follow-up examination (right) by reader 2. This resulted in the assignment of SD as response classification for both types of measurements by reader 2