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. 2021 Nov 15;11:650678. doi: 10.3389/fonc.2021.650678

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Copyright © 2021 Lin, Xu, Li, Yao, Yu, Zhu and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comprehensive analysis of OLFML2B. (A) Expression levels of five mRNA types which contained basal squamous, luminal, Luminal infiltrated, luminal papillary, and neuronal subtypes, respectively. (B) The expression levels of the five immunophenotypes were C1 (wound healing), C2 (IFN-gamma dominant), C3 (inflammatory), C4 (lymphocyte depleted), C6 (TGF-b dominant). (C) A bar chart of the proportion of genomic changes in four cohorts of OLFML2B. (D) According to the Genome alteration of OLFML2B, the patients were divided into two groups for Kaplan–Meier analysis. (E) Comparison of methylation levels of OLFML2B in normal and tumor tissues. P < 0.05 indicates that it is statistically significant.