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. 2021 Nov 15;12:789454. doi: 10.3389/fimmu.2021.789454

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Copyright © 2021 Nabi, Lewin, Collantes, Chouljenko and Kousoulas

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ocular infiltration and score following inhibition of T cell migration. T cell migration in mouse eyes was inhibited by the administration of FTY720 on ocular surfaces. (A) γδT cell infiltration. (B) Neutrophil infiltration at 5DPI. (C) Ocular score following infection. (D) IFM on a representative OCT section for detection of γδT and neutrophil cell infiltration in ocular tissues. (E) IFM for CD31 and LYVE-1 expression. (F) Viral DNA copies in TG using qPCR. *<P=0.05, **<P=0.005 using the Mann-Whitney test, n=5/group. ns, Non-Significant.