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. 2021 Nov 15;9:763267. doi: 10.3389/fcell.2021.763267

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Copyright © 2021 Cao, Ma, Mo, Shu, Liu, Ye and Gui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ScRNA-seq profiles of P20 WT and SCARKO testicular cells and cell type identification. (A) Heatmap of differentially expressed genes (DEGs) from the five major cell types. Top: cell cluster; right: major cell types and representative enriched marker genes for each cell type. (B) Representative markers for each cell type. (C,D) tSNE and clustering analysis of combined single-cell transcriptome data from P20 WT and SCARKO testicular cells. Each dot represents a single-cell and cell clusters are distinguished by colors. (E) The percentage of cell numbers in each cluster in P20 WT and SCARKO testicular cells. (F) The number of DEGs (up and down-regulated) in each cluster in SCARKO testicular cells.