Table 1.

Betacoronaviruses known to bind the ACE2 receptor

Virus	Host	Acc. Num.	References
SARS-CoV	Human	P59594	[18]a
SARS-CoV-2	Human	P0DTC2	[19]a
GXP2V	Pangolin	A0A6G9KP06	[20]a
MP789	Pangolin	A0A6M3G9R1	[21]a
RS7327	Bat	A0A2D1PXC0	[16]a
YN2018B	Bat	A0A4Y6GL47	[15]a
Rs9401	Bat	A0A2D1PXD5	[15]b
WIV16	Bat	A0A0U2IWM2	[22]a
Rs4874	Bat	A0A2D1PX97	[15]b
Rs3367	Bat	U5WHZ7	[15]b
WIV1	Bat	U5WI05	[23]a
Rs4084	Bat	A0A2D1PX29	[16]a
RsSHC014	Bat	U5WLK5	[24]a
Rs4231	Bat	A0A2D1PXA9	[16]a
RaTG13	Bat	A0A6B9WHD3	[25]a

Cited evidence for ACE2 usage based either on demonstration of binding^a or bioinformatic prediction of binding^b. In cases where the prediction was made prior to demonstration, the citation for the demonstration is shown. Others have hypothesized that the additional pangolin coronaviruses included in our analysis also bind ACE2, however, this has not yet been investigated.