Table 2.

Values (V) representing the combined properties of HP and MW for pairs of amino acids.

Residue	G	A	L	M	F	W	K	Q	E	S	P	V	I	C	Y	H	R	N	D	T
G	0.306
A	7.978	15.650
L	30.537	38.208	60.767
M	26.221	33.893	56.452	52.136
F	38.486	46.157	68.716	64.400	76.665
W	48.653	56.325	78.883	74.568	86.832	97.000
K	−7.763	−0.091	22.468	18.152	30.417	40.584	−15.832
Q	−3.287	4.385	26.943	22.628	34.892	45.060	−11.356	−6.881
E	2.927	10.598	33.157	28.842	41.106	51.274	−5.142	−0.667	5.547
S	−1.016	6.656	29.214	24.899	37.163	47.331	−9.085	−4.609	1.605	−2.338
P	−11.842	−4.170	18.388	14.073	26.337	36.505	−19.911	−15.436	−9.222	−13.164	−23.991
V	20.382	28.053	50.612	46.297	58.561	68.729	12.313	16.788	23.002	19.059	8.233	40.457
I	30.233	37.905	60.463	56.148	68.412	78.580	22.164	26.639	32.853	28.911	18.084	50.308	60.159
C	13.724	21.396	43.954	39.639	51.903	62.071	5.655	10.131	16.344	12.402	1.576	33.799	43.651	27.142
Y	21.622	29.294	51.852	47.537	59.801	69.969	13.553	18.029	24.242	20.300	9.474	41.697	51.548	35.040	42.938
H	−11.262	−3.590	18.969	14.653	26.917	37.085	−19.331	−14.855	−8.641	−12.584	−23.410	8.814	18.665	2.156	10.054	−22.830
R	−5.718	1.954	24.512	20.197	32.461	42.629	−13.787	−9.312	−3.098	−7.040	−17.866	14.357	24.209	7.700	15.598	−17.286	−11.742
N	−8.426	−0.754	21.805	17.489	29.754	39.921	−16.495	−12.019	−5.805	−9.748	−20.574	11.650	21.501	4.992	12.890	−19.994	−14.450	−17.158
D	−16.843	−9.171	13.388	9.072	21.336	31.504	−24.912	−20.436	−14.222	−18.165	−28.991	3.233	13.084	−3.425	4.473	−28.411	−22.867	−25.575	−33.992
T	3.683	11.354	33.913	29.597	41.862	52.029	−4.387	0.089	6.303	2.360	−8.466	23.758	33.609	17.100	24.998	−7.886	−2.342	−5.050	−13.467	7.059

The values on the diagonal were calculated using Equation (1) and the lower triangle values represent the means of the individual values for a given pair of residues.