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. 2021 Nov 12;8(6):rbab062. doi: 10.1093/rb/rbab062

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Preparation of MnO-TETT-FA NPs as glioblastoma-distinct MRI contrast agents [29]. (A) Schematic illustration of MnO-TETT-FA preparation and imaging mechanism. (B) r₁ relaxivities of MnO-TETT (top) and MnO-TETT-FA (bottom) NPs. (C) In vivo MRI of C6-bearing mice. (D) Quantification of the signal intensity in the tumour area at different time points. Reproduced with permission [29]. Copyright 2014, American Chemical Society. FA, folic acid; MRI, magnetic resonance imaging; NPs, nanoparticles; TETT, N-(trimethoxysilylpropyl) ethylene diamine triacetic acid