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. 2021 Nov 12;8(6):rbab062. doi: 10.1093/rb/rbab062

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Lf-M-PAEEP-PLLA-NPs were used as glioblastoma-targeted MRI contrast agents [33]. (A) Schematic illustration of Lf-M-PAEEP-PLLA-NP preparation. (B) In vivo MRI of C6-bearing rats. (C) Prussian blue staining assays of c6-bearing rats after Lf-M-PAEEP-PLLA-NP injection. (D) Quantification of the signal enhancement in the tumour area at different time points. Reproduced with permission [33]. Copyright 2016, Springer Nature. Lf, lactoferrin; MRI, magnetic resonance imaging; NPs, nanoparticles; PAEEEP-PLLA, amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide)