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. 2021 Nov 12;8(6):rbab062. doi: 10.1093/rb/rbab062

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Gd@C₈₂-Ala-PEG-cRGD-NOTA-⁶⁴Cu were used as a PET/MRI nanoprobe for GBM-targeted imaging [27]. (A) Schematic diagram of Gd@C₈₂-Ala-PEG-cRGD-NOTA-⁶⁴Cu biosynthesis and function. (B) In vivo PET imaging of MDA-MB-23 tumour-bearing mice. (C) In vivo PET and MR imaging of U87 MG-bearing mice after injection of Gd@C₈₂-Ala-PEG-cRGD-NOTA-⁶⁴Cu. Reproduced with permission [27]. Copyright 2019, American Chemical Society. GBM, glioblastoma; MRI, magnetic resonance imaging; PEG, polyethylene glycol; PET, positron emission tomography; RGD, arginine-glycine-aspartic