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. 2021 Jul 8;113(12):1648–1669. doi: 10.1093/jnci/djab131

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© The Author(s) 2021. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Average annual percent change (AAPC) in age-standardized, delay-adjusted incidence rates for 2013-2017 for all sites and the 18 most common cancers in men and women and age-standardized death rates for 2014-2018 for the 19 most common cancer deaths in men and the 20 most common cancer deaths in women, all ages, all races or ethnicities combined, by sex. The AAPC was a weighted average of the annual percent change (APCs) over the fixed 5-year interval (incidence, 2013-2017; mortality, 2014-2018) using the underlying joinpoint regression model, which allowed up to 3 different APCs, for the 17-year period 2001-2017 for incidence and 18-year period 2001-2018 for mortality. ^aAAPCs were statistically significantly different from zero (2-sided P < .05), using a t test when the AAPC laid entirely within the last joinpoint segment and a z-test when the last joinpoint fell within the last 5 years of data, and are depicted as solid-colored bars; AAPCs with hash marks were not statistically significantly different from zero (stable). NOS = not otherwise specified.