Summary of strategy and results from MR and MR-PheWAS analyses. ASCVD: atherosclerotic cardiovascular disease, CI: confidence interval, eMERGE: electronic MEdical Records and GEnomics, Lp(a): lipoprotein(a), MR: Mendelian randomization, MVP: Million Veteran Program, OR: odds ratio, SD: standard deviation, SNV: single-nucleotide variant, UK: United Kingdom. The images in the MR-PheWAS box were created with BioRender.com.