HJC0416 inhibits LX-2 and HSC-T6 cell viability and causes cell cycle arrest
(A) LX-2 and (B) HSC-T6 cells were treated with a series of concentrations of HJC0416 for 48 hours, and cell viability was determined using alamar blue assay. (C) HJC0416 induced cell cycle arrest at the S phase in LX-2 cells. (D) HJC0416 decreased Hoechst dsDNA staining, and increased staining for Yo-Pro-1 and Propidium Iodide, markers of apoptosis. The results are representative of at least three different experiments.