Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 15;15:745050. doi: 10.3389/fnins.2021.745050

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Dobryakova, Spivak, Zaichenko, Koryagina, Markevich, Stepanichev and Bolshakov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A–C) Show immunostaining of ChAT in the medial septal area of rats treated with PBS (A), 192IgG-saporin (B), or 192IgG-saporin and NGF-carrying virus (SAP-NGF) (C). (D) Shows the number of ChAT-positive neurons counted in the medial septum area. Bar, 200 μm. (E) Demonstrates acetylcholinesterase activity in rat hippocampi injected with PBS (PBS-GFP, n = 10), 192IgG-saporin (SAP-GFP, n = 9), and with 192IgG-saporin and NGF-carrying virus (SAP-NGF, n = 10) 1.5 month postinjection. Each point represents mean ± SEM. ^∗Significant differences against the saline group, p < 0.05.