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Sequence of oligonucleotides 17–19 followed by preparation to the corresponding 17″-19 analogues: (i) T4-RNA ligase, bisphosphate 21; then T4-PNK, ATP; (ii) xrn-1, then dPAGE. The table inset shows the calculated yields for the observed fragments, corresponding to stalling at 8-oxoG.
