Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Putative mechanisms underlying low-dose piperlongumine reducing cerebral ischemic injury in HFD-fed mice. High-fat diet impaired endothelial progenitor cell function, decreased the ischemic angiogenesis, increased cerebral infarct volumes, and reduced the corresponding neurobehavioral outcomes in mice. Low-dose piperlongumine reduces cerebral ischemic injury via rescuing impaired EPC-mediated angiogenesis in HFD-fed mice.
